Sleep-related breathing disorders
Obstructive Sleep Apnea
Your airway repeatedly narrows or closes during sleep, cutting airflow, dropping oxygen and fragmenting sleep. It is common, underdiagnosed and very treatable.
Overview
Obstructive sleep apnea (OSA) happens when the muscles that hold your throat open relax too much during sleep. The airway narrows or collapses, breathing becomes shallow (a hypopnea) or stops (an apnea) for 10 seconds or longer, and your brain briefly wakes you to reopen it. This can happen dozens of times an hour without you remembering any of it.
The repeated drops in oxygen and constant micro-awakenings mean sleep is never fully restorative. Many people notice loud snoring, gasping, morning headaches and heavy daytime sleepiness, although some people, especially women, report fatigue, insomnia or low mood instead.
Untreated OSA is linked to high blood pressure, heart disease, atrial fibrillation, stroke, type 2 diabetes and drowsy-driving crashes. The good news is that effective treatments exist, from CPAP and oral appliances to weight loss, newer medication and implanted nerve stimulators, and most people feel noticeably better once their breathing is stable at night.
A 2019 analysis in The Lancet Respiratory Medicine estimated that about 936 million adults aged 30 to 69 worldwide have mild to severe obstructive sleep apnea.
Common symptoms
- Loud, frequent snoring
- Pauses in breathing, choking or gasping noticed by a bed partner
- Waking with a dry mouth or sore throat
- Morning headaches
- Excessive daytime sleepiness or dozing off while reading, watching TV or driving
- Unrefreshing sleep even after a full night in bed
- Waking up often to urinate at night
- Trouble concentrating, poor memory or irritability
- Waking up with a racing heart or a sensation of choking
Causes and risk factors
- Excess body weight, especially fat around the neck and tongue
- Narrow airway, large tonsils, a recessed jaw or a large tongue
- Male sex, and in women, the period after menopause
- Older age
- Family history of sleep apnea
- Alcohol, sedatives or opioids that relax throat muscles
- Smoking
- Nasal congestion or obstruction
- Sleeping on your back
- Conditions such as high blood pressure, type 2 diabetes, heart failure, hypothyroidism and polycystic ovary syndrome
How it is diagnosed
A clinician usually starts with your sleep history and questionnaires such as STOP-Bang (a screening tool for OSA risk) and the Epworth Sleepiness Scale. These help decide who needs testing, but they cannot diagnose OSA on their own.
Diagnosis requires a sleep study. An in-lab polysomnogram records brain waves, breathing, oxygen, heart rhythm and leg movements overnight. For many adults with a high likelihood of moderate to severe OSA and no major heart or lung disease, a home sleep apnea test that measures breathing and oxygen is an acceptable first step.
Results are reported as the apnea-hypopnea index (AHI), the number of breathing events per hour of sleep. In adults, fewer than 5 is considered normal, 5 to 14 is mild, 15 to 29 is moderate and 30 or more is severe. OSA is diagnosed with an AHI of 15 or more, or an AHI of 5 or more together with symptoms such as sleepiness or related conditions such as high blood pressure.
Treatment options
CPAP or APAP
A machine delivers gentle air pressure through a mask to keep your airway open. It is the most effective and most studied treatment, and auto-adjusting machines (APAP) are widely used.
Oral appliance therapy
A custom mouthpiece made by a dentist moves your lower jaw forward to keep the airway open. It is an option for mild to moderate OSA or for people who cannot tolerate CPAP.
Weight loss
Losing weight can reduce the number of breathing events and sometimes resolves mild OSA.
Tirzepatide (Zepbound)
In December 2024 the FDA approved this weekly injection for moderate to severe OSA in adults with obesity, used alongside diet and exercise.
Positional therapy
Devices or techniques that keep you off your back help people whose apnea occurs mainly when sleeping supine.
Hypoglossal nerve stimulation
An implanted device stimulates the nerve that moves the tongue forward with each breath. It is for selected adults who cannot use CPAP.
Surgery
Procedures on the nose, palate, tonsils or jaw (such as maxillomandibular advancement) can help selected people, particularly those with a clear anatomical cause.
Treating nasal congestion
Managing allergies or a deviated septum can make CPAP more comfortable and improve breathing.
What you can do yourself
- Use your CPAP every night and for the whole night, including naps
- Avoid alcohol and sedating medicines in the hours before bed
- Work towards a healthy weight with your care team
- Try sleeping on your side if your apnea is worse on your back
- Stop smoking
- Keep a regular sleep schedule and aim for at least 7 hours
- Do not drive or operate machinery when you feel drowsy
When to see a doctor
- A bed partner notices you stop breathing, choke or gasp in your sleep
- You feel sleepy during the day despite spending enough time in bed
- You have nodded off while driving or nearly had a crash
- You snore loudly and have high blood pressure, heart disease, atrial fibrillation or diabetes
- Your CPAP feels uncomfortable or you have stopped using it
Frequently asked questions
Can you have sleep apnea without snoring?
Yes. Snoring is the most common sign, but not everyone with obstructive sleep apnea snores loudly, and some people, often women, mainly notice fatigue, insomnia, headaches or low mood. If you are tired despite enough sleep, it is worth asking about a sleep study even if no one has heard you snore.
Is a home sleep test as good as a lab study?
For many adults with a high likelihood of moderate to severe OSA and no major heart, lung or neurological disease, a home sleep apnea test is an accepted way to diagnose it. Home tests can underestimate mild apnea because they do not measure actual sleep, so a negative or borderline result in someone with symptoms often needs an in-lab study.
What do the AHI numbers mean?
The apnea-hypopnea index counts breathing pauses and shallow breaths per hour of sleep. In adults, 5 to 14 is mild, 15 to 29 is moderate and 30 or more is severe. Your CPAP machine also reports a residual AHI, and a number under 5 on treatment generally means the pressure is controlling your apnea well.
Will losing weight cure my sleep apnea?
Weight loss often reduces the severity of OSA and can resolve it for some people, especially those with mild disease. It does not work for everyone because jaw shape, airway size and other factors also play a role. Keep using your prescribed treatment until a repeat sleep study shows it is no longer needed.
Is untreated sleep apnea dangerous?
Over time, untreated moderate to severe OSA is associated with high blood pressure, heart disease, stroke, atrial fibrillation and type 2 diabetes. The daytime sleepiness it causes also raises the risk of motor vehicle crashes. Treatment lowers blood pressure in many people and improves sleepiness and quality of life.
Sources
This page is general information, not a diagnosis or medical advice. Read our medical disclaimer.